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GENETICS AND PATHOBIOLOGY OF VASCULAR COGNITIVE IMPAIRMENT

Published on AidPage by IDILOGIC on Jun 24, 2005
Administered by:

Department of Health and Human Services, National Institutes of Health, National Institutes of Health
(see all US Federal Agencies)

Explore all postings for this grant program:
  • Original Grant - Aug 31, 2004
Applications Due:


Multiple Receipt Dates - See Link to Full Announcement for details.

total funding: $2,250,000
max award: $200,000
min award: none
cost sharing, matching: No
number of awards: Not Available
type of funding: Grant
Description:

The purpose of this Program Announcement with set-aside funds (PAS) is to
invite applications to study the biological basis of vascular cognitive
impairment (VCI). VCI causes a burden of illness similar to that caused by
Alzheimers disease (AD), but has been far less well-studied. Recently,
however, some important strides have been made in understanding the etiology
of VCI. These include the discovery of a monogenic form of vascular
dementia, CADASIL, and identification of the causative gene as Notch 3. In
addition, MRI and other pathological data have provided a clearer delineation
of the various clinical subtypes of VCI, and awareness of the synergistic
interaction between vascular and classical Alzheimers pathologies in
producing cognitive impairment. The goal of this PAS is to build on these
first critical achievements to obtain a better understanding of the cellular
and molecular mechanisms causing vascular, neural, and glial dysfunction in
human VCI and animal models of VCI.

Who can apply:

Anyone/General Public
City Or Township Governments
County Governments
Federally Recognized Indian Tribal Governments
Independent School Districts
Individual/Family
Minority Group
Native American Organization
Non-Government - General
Nonprofits Having A 501(C)(3) Status With The IRS, Other Than Institutions Of Higher Education
Nonprofits That Do Not Have A 501(C)(3) Status With The IRS, Other Than Institutions Of Higher Education
Other Private Institution/Organization
Private Institutions Of Higher Education
Private Nonprofit Institution/Organization (Includes Institutions Of Higher Education, Hospitals)
Profit Organization
Public And State Controlled Institutions Of Higher Education
Public Housing Authorities/Indian Housing Authorities
Quasi-Public Nonprofit Institution/Organization
Small Business (Less Than 500 Employees
Special District Governments
State (Includes District Of Columbia; Includes Institutions Of Higher Education And Hospitals)
U.S. Territories And Possessions (Includes Institutions Of Higher Education, Hospitals)

Eligible functional categories:
Funding Sources:

Aging Research
Extramural Research Programs in the Neurosciences and Neurological Disorders
Heart and Vascular Diseases Research
Lung Diseases Research

More Information:

http://grants.nih.gov/grants/guide/pa-files/PAS-04-149.html

If you have problems accessing the full announcement, please contact: NIH OER Webmaster

Address Info:

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